Summary
Organ-on-Chip (OoC) is a game-changing approach in which human cells are cultured in microfluidic chips simulating and predicting the response of healthy and diseased human tissues. OoC has the potential to revolutionize today’s biomedical testing procedures that often involve ethically challenged animal testing and, most importantly, lead to variable results. Despite its promise, OoC adoption is hampered by profound technical and functional limitations. In this multidisciplinary program, engineers and biomedical researchers join forces with 25 end users to overcome these limitations by developing a novel, Standardized, open and Modular OoC Approach to Recapitulate Tissues (“SMART OoC”).